Endocrine Abstracts

Introduction: Type 2 deiodinase (D2) catalyses intracellular T3 production in several human tissues including pituitary gland, hence occupying an important role in the feedback regulation of TSH secretion. Although several previous researches have shown that Thr92Ala D2 polymorphism with decreased D2 enzymatic activity influences the levothyroxine dose requirement and the set point of the hypothalamus–pituitary–thyroid axis for postoperative TSH suppressiv...

Background: The severity of non-alcoholic fatty liver disease (NAFLD) in type 2 diabetes mellitus (T2DM) population compared with that in normal glucose tolerance (NGT) individuals has not yet been assessed by a quantitative method. We investigated the prevalence and the severity of NAFLD in a T2DM population using controlled attenuation parameter (CAP).Methods: Subjects who underwent testing for biomarkers related to T2DMand CAP using Fibroscan during a...